Curriculum Vitae
Curriculum Vitae
Education
Institute of Science Tokyo (Tokyo, Japan) / Apr 2025 – Present
School of Life Science and Technology
Doctoral Program in Engineering
Institute of Science Tokyo (Tokyo, Japan) / Apr 2023 – Mar 2025
School of Life Science and Technology
Master of Engineering
Tokyo Institute of Technology (Tokyo, Japan) / Apr 2020 – Mar 2023 (graduated one year early)
School of Life Science and Technology
Bachelor of Engineering
Research Experience
Institute of Science Tokyo (Tokyo, Japan) / Apr 2025 – Present
Doctoral Thesis Research, under Prof. Dr. Kazushi Kinbara
National Institute of Advanced Industrial Science and Technology (Tsukuba, Japan) / Apr 2025 – Present
Research Trainee, under Prof. Dr. Shunsuke Tomita
Universität Basel (Basel, Switzerland) / Jun 2024 – Dec 2024
Visiting Research Student, under Prof. Dr. Thomas R. Ward
Institute of Science Tokyo (Tokyo, Japan) / Apr 2023 – Mar 2025
Master’s Thesis Research, under Prof. Dr. Kazushi Kinbara
“Strategic Design of PEG-Appended Molecules and Functionalization of Artificial Cell Membranes”
Tokyo Institute of Technology (Tokyo, Japan) / Oct 2021 – Mar 2023
Bachelor’s Thesis Research, under Prof. Dr. Kazushi Kinbara
“Functionalization of Lipid Bilayers by Rigid π-Conjugated Macrocycles”
Publications
5. Rei Hamaguchi, Ai Kohata, Mafumi Hishida, Hiroka Sugai, Mitsunori Ikeguchi*, and Kazushi Kinbara*
Effect of PEG Chain Length on the Water Solubility of Monodisperse PEG-Appended Molecules
J. Phys. Chem. B 2026, 130, 5661–5670. DOI: 10.1021/acs.jpcb.5c08697
4. Ai Kohata*, Rei Hamaguchi, and Kazushi Kinbara*
Self-Assembly Behavior of Monodisperse PEG Amphiphiles Bearing Hydrophobic Units with Distinct Molecular Shapes in Water
ChemistryOpen 2026, 15, e70214. DOI: 10.1002/open.70214
3. Rei Hamaguchi, Damian Alexander Graf, Kazushi Kinbara*, and Thomas R. Ward*
Programmable Artificial-Cellular Membrane Dynamics via Ring-Closing Metathesis
J. Am. Chem. Soc. 2025, 147, 39204–39211. DOI: 10.1021/jacs.5c10187
Swiss Nanoscience Institute News: Controlled phase separation in membranes (Oct 21, 2025)
Science Tokyo News: Chemistry meets biology: controlling artificial cell membranes through catalysis (Nov 27, 2025)
CHIMIA 2026, 80, No. 1/2., Swiss Science Concentrates, A CHIMIA Column
2. Kylie Chinner, Niklas Grabicki, Rei Hamaguchi, Mitsunori Ikeguchi, Kazushi Kinbara, Sayaka Toyoda, Kohei Sato*, and Oliver Dumele*
Nanohoops in membranes: confined supramolecular spaces within phospholipid bilayer membranes
Chem. Sci. 2024, 15, 16367–16376. DOI: 10.1039/D4SC03408B
1. Junya Adachi, Haruka Oda, Toshiaki Fukushima*, Beni Lestari, Hiroshi Kimura, Hiroka Sugai, Kentaro Shiraki, Rei Hamaguchi, Kohei Sato, and Kazushi Kinbara*
Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection
Anal. Chem. 2023, 95, 5196–5204. DOI: 10.1021/acs.analchem.2c04133
Presentations
12. “Computational and Experimental Study on the Chain Length-Dependent Water Solubility of Monodisperse PEG-Appended Molecules”, The 75th Symposium on Macromolecules, Katsushika Campus, Tokyo University of Science, Tokyo, September 2026.
11. “Hydration Dynamics of Monodisperse PEG-Appended Molecules: A Molecular Dynamics Simulation Study”, The 36th Bio-Polymer Symposium, Ookayama Campus, Institute of Science Tokyo, Tokyo, July 2026.
10. “Development of Transition-Metal Catalysts Functioning at the Lipid Bilayer Interface”, The 37th Summer School for Young Researchers of the Division of Biofunctional Chemistry, Tosei Hotel & Seminar Makuhari, Chiba, July 2026.
9. “Ring-Closing Metathesis–Driven Lipid Domain Reorganization by a Supramolecularly Anchored Artificial Metalloenzyme”, CEMSupra 2026, Ito International Research Center, The University of Tokyo, Tokyo, January 2026.
8. “Ring-Closing Metathesis–Driven Dynamic Reorganization of Lipid Domains toward Artificial Cell Engineering”, 13th Workshop on Organic Chemistry for Junior Chemists (WOCJC-13), National Tsing Hua University, Hsinchu, Taiwan, January 2026.
7. “Regulation of Artificial-Cellular Membrane Dynamics via Ring-Closing Metathesis”, Bio-Polymer Symposium 2025, Ookayama Campus, Institute of Science Tokyo, Tokyo, July 2025.
6. “Regulation of Membrane-Raft Dynamics via a Transition Metal-Catalyzed Reaction”, ISMSC 2025 Kyoto, ROHM Theatre Kyoto, Kyoto, May 2025.
5. “Control of the dynamics of an artificial cell-membrane via a transition metal-catalyzed reaction”, The 105th CSJ Annual Meeting, Senriyama Campus, Kansai University, Osaka, March 2025.
4. “Prediction and experimental validation of chain length-dependent water solubility of monodisperse-PEG-appended molecules”, The 26th Annual Meeting of JSTC, University of Tsukuba, Ibaraki, May 2024.
3. “Theoretical and experimental studies on the water solubility of monodisperse PEGylated molecules carrying PEG chain with different length”, The 104th CSJ Annual Meeting, Funabashi Campus, Nihon University College of Science and Technology, Chiba, March 2024.
2. “Development of Monodisperse PEG-appended Hoveyda–Grubbs-type Catalysts Embedded in Lipid Bilayers”, The 4th Molecular Engine Workshop, Kyodo Omachi Building, Akita, September 2023.
1. “Functionalization of Lipid Bilayers with Monodisperse PEGylated Amphiphilic Molecules”, The 33rd Symposium on Physical Organic Chemistry, Okayama Convention Center, Okayama, September 2023.
Fellowships, Scholarships, and Awards
· Japan Society for the Promotion of Science (JSPS) Research Fellowship for Young Scientists (DC1) / Apr 2025 – present
· TAC-MI Special Award for Excellence / Jun 2026
· Oral Presentation Award, WOCJC-13 / Jan 2026
· 33rd Ohsumi Journal Award / Dec 2025
· Student Outstanding Poster Award, 35th Bio-Polymer Symposium / Jul 2025
· Teijin Kumura Scholarship / Apr 2023 – Mar 2025